X-linked hypophosphatemia. Genetic and clinical correlates
J. D. Hanna, K. Niimi and J. C. Chan
Department of Pediatrics, Virginia Commonwealth University's Medical College of Virginia, Richmond.
X-linked hypophosphatemia is a hereditary form of rickets that results from
an isolated renal tubular wasting of phosphate. The clinical features
unique to this disorder, and the recent advances in our understanding of
vitamin D metabolism and molecular genetics in X-linked hypophosphatemia
are reviewed. Finally, a succinct critique of the controversial treatment
modalities round up this review.
