Zinc deficiency. A public health problem?
H. H. Sandstead
Department of Preventive Medicine and Community Health, University of Texas Medical Branch, Galveston 77550-2774.
Zinc deficiency occurs in individuals and populations whose diets are low
in sources of readily bioavailable zinc such as red meat, and high in
unrefined cereals that are rich in phytate and dietary fibers. Dietary zinc
deficiency was described nearly three decades ago among the poor of the
Middle East. It is now known to occur in children and adolescents from
widely diverse areas including Egypt, Iran, Turkey, China, Yugoslavia,
Canada, and the United States; and among pregnant women from Iran, Turkey,
the United Kingdom, Australia, and the United States. Major manifestations
include retarded growth and development and an increased incidence of
pregnancy complications. Other manifestations may include suppressed
immunity, poor healing, dermatitis, and impairments in neuropsychological
functions. Precise information as to the numbers of people affected by
dietary zinc deficiency is not available. Even so the nature of diets
associated with zinc deficiency suggests that mild deficiency is common in
some populations.
Role of Zinc Administration in Prevention of Childhood Diarrhea and Respiratory Illnesses: A Meta-analysis
Aggarwal et al.
Pediatrics 2007;119:1120-1130.
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Effect of Beef and Soy Proteins on the Absorption of Non-Heme Iron and Inorganic Zinc in Children.
Etcheverry et al.
J. Am. Coll. Nutr. 2006;25:34-40.
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UNDERNUTRITION AS AN UNDERLYING CAUSE OF MALARIA MORBIDITY AND MORTALITY IN CHILDREN LESS THAN FIVE YEARS OLD
CAULFIELD et al.
Am J Trop Med Hyg 2004;71:55-63.
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Effect of zinc supplementation started during diarrhoea on morbidity and mortality in Bangladeshi children: community randomised trial
Baqui et al.
BMJ 2002;325:1059-1059.
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Predictors of Micronutrient Status among Six- to Twelve-Month-Old Breast-Fed Ghanaian Infants
Lartey et al.
J. Nutr. 2000;130:199-207.
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Adding zinc to prenatal iron and folate supplements improves maternal and neonatal zinc status in a Peruvian population
Caulfield et al.
Am. J. Clin. Nutr. 1999;69:1257-1263.
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Impact of Zinc Supplementation on Morbidity From Diarrhea and Respiratory Infections Among Rural Guatemalan Children
Ruel et al.
Pediatrics 1997;99:808-813.
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