This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Frederic Gottrand, MD; Olivier Bernard, MD; Michelle Hadchouel, MD; Daniele Pariente, MD; Frederic Gauthier, MD; Daniel Alagille, MD

Am J Dis Child. 1991;145(2):213-215.

Abstract
• Bacterial cholangitis is a frequent complication of successful surgical repair of biliary atresia, occurring in 93% of patients before the age of 1 year, but thought to be rare after 2 years of age. Among 76 children free of jaundice more than 5 years after operation, four presented with late cholangitis (7 to 13.5 years old), consisting of fever, jaundice, and abdominal pain with biochemical features of an inflammatory process and cholestasis. Liver biopsy specimens consistently demonstrated histological features of cholangitis, growth of microorganisms, or both. Cholangitis subsided spontaneously in one patient or in response to intravenous administration of antibiotics. Cholangiography consistently demonstrated biliary abnormalities but no definite obstruction to the bilioenteric anastomosis. All the children had good hepatic function 3 weeks to 4 years after the episode of cholangitis. These results suggest that cholangitis may occur several years after surgery but does not seem to alter prognosis.

(AJDC. 1991;145:213-215)

Author Affiliations
From the Units of Hepatology (Drs Gottrand, Bernard, and Alagille), Institut National de la Santé et de Recherche Médicale U56 (Dr Hadchouel), Radiology (Dr Pariente), and Surgery (Dr Gauthier), Department of Pediatrics, Bicêtre Hospital, Le Kremlin-Bicêtre, France.

Footnotes
Accepted for publication September 5,1990.

Presented as a brief oral communication before the French Society of Gastroenterology and Paediatric Nutrition, Grenoble, France, April 29, 1988.

Reprint requests to Department of Pediatrics, Claude Huriez Hospital, University Hospital of Lille, 59037 Lille Cédex, France (Dr Gottrand).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Pathogenesis and Clinical Presentation of Bile Duct Calculi
Mack
SURG INNOV 1995;2:76-84.
ABSTRACT