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Lumbar Puncture Frequency and Cerebrospinal Fluid Analysis in the Neonate
Jeffrey Schwersenski, MD;
Lester McIntyre, MD;
Charles R. Bauer, MD
Am J Dis Child. 1991;145(1):54-58.
Abstract
• A prospective study was performed to assess the frequency and diagnostic utility of lumbar punctures in neonates both during their first week of life and thereafter. During the two 6-month periods from January 1,1985 to June 30,1985, and February 1,1986 to July 31,1986,712 neonates underwent 728 lumbar punctures during their first week of life primarily as part of the evaluation for suspected infection, either congenital or postnatal. There were eight patients with positive spinal fluid cultures in the first week of life, but only one patient simultaneously had a positive blood culture and a clinical course consistent with meningitis. In contrast, a considerably higher yield, approximating five times that of the first week of life, was obtained in patients undergoing a lumbar puncture after the first week of life.
(AJDC. 1991;145:54-58)
Author Affiliations
From the Division of Neonatology, Department of Pediatrics, University of Miami, Fla.
Footnotes
Accepted for publication June 4,1990.
Read in part before the Southern Society for Pediatric Research, New Orleans, La, February 7,1986.
Reprint requests to Department of Pediatrics (R-131), University of Miami, PO Box 016960, Miami, FL 33101 (Dr Bauer).
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