Treatment of croup. A critical review
N. S. Skolnik
Department of Family Medicine, Thomas Jefferson University, Philadelphia, Pa.
Although viral croup is the most common form of airway obstruction in
children 6 months to 6 years of age, there is debate regarding medical care
for the hospitalized patient. A complete review of the English-language
literature from 1960 to 1988 was performed, using both manual and Medline
searches. Critical review shows that laryngotracheitis and spasmodic croup,
previously emphasized in the literature as having distinct etiologies, most
likely are two ends of a broad spectrum in the clinical presentation of a
single disease. Critical assessment of all prospective randomized
double-blind placebo-controlled trials reported during the study period
shows that there is little information on the use of humidified air or
supplemental oxygen, that racemic epinephrine hydrochloride is of
well-demonstrated efficacy, and that dexamethasone phosphate at a dose
greater than 0.3 mg/kg is effective in decreasing the length and severity
of respiratory symptoms associated with viral croup.
Humidified air inhalation for treating croup: a systematic review and meta-analysis
Moore and Little
Fam Pract 2007;24:295-301.
ABSTRACT
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Controlled Delivery of High vs Low Humidity vs Mist Therapy for Croup in Emergency Departments: A Randomized Controlled Trial
Scolnik et al.
JAMA 2006;295:1274-1280.
ABSTRACT
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Parainfluenza Viruses
Henrickson
Clin. Microbiol. Rev. 2003;16:242-264.
ABSTRACT
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The management of croup
Brown
Br Med Bull 2002;61:189-202.
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Outpatient Treatment of Moderate Croup With Dexamethasone: Intramuscular Versus Oral Dosing
Rittichier and Ledwith
Pediatrics 2000;106:1344-1348.
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The effectiveness of glucocorticoids in treating croup: meta-analysis
Ausejo et al.
BMJ 1999;319:595-600.
ABSTRACT
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The Treatment of Croup with Glucocorticoids
Jaffe
NEJM 1998;339:553-555.
FULL TEXT
Double blind placebo controlled trial of nebulised budesonide for croup • Commentary
Godden et al.
Arch. Dis. Child. 1997;76:155-158.
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Corticosteroids in the management of croup
Doull
BMJ 1995;311:1244-1244.
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Nebulized Budesonide for Children with Mild-to-Moderate Croup
Klassen et al.
NEJM 1994;331:285-289.
ABSTRACT
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Aerosolized Steroids for Croup
Landau and Geelhoed
NEJM 1994;331:322-323.
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The Old and New of Acute Laryngotracheal Infections
Cunningham
CLIN PEDIATR 1992;31:56-64.
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