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Daniel V. Schidlow, MD; Howard B. Panitch, MD; Nayere Zaeri, MD; Joseph Zenel, MD; Brad E. Alpert, MD

Am J Dis Child. 1989;143(9):1030-1032.

Abstract
• Sixteen patients with cystic fibrosis experienced vasculitic rashes of the lower extremities that resembled hypergammaglobulinemic purpura. The rashes were associated with increased serum gammaglobulin G levels and rather severe lung disease. The rashes are probably the expression of chronic lung infection and high antigenic load in these patients. Their appearance was associated, in most cases, with poor long-term survival.

(AJDC. 1989;143:1030-1032)

Author Affiliations
From the Departments of Pediatrics (Drs Schidlow, Panitch, Zenel, and Alpert) and Pathology (Dr Zaeri), St Christopher's Hospital for Children, Temple University School of Medicine, Philadelphia, Pa. Dr Zenel is now in private pediatric practice in York, Pa.

Footnotes
Accepted for publication January 11, 1989.

Reprint requests to Pediatric Pulmonary and Cystic Fibrosis Center, St Christopher's Hospital for Children, Fifth Street and Lehigh Avenue, Philadelphia, PA 19133 (Dr Schidlow).

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