Manganese absorption from human milk, cow's milk, and infant formulas in humans
L. Davidsson, A. Cederblad, B. Lonnerdal and B. Sandstrom
Department of Clinical Nutrition, University of Gothenburg, Sahlgrenska Hospital, Goteborg, Sweden.
Manganese absorption from human milk, cow's milk, and infant formulas was
studied in humans by using extrinsic labeling of the diets with manganese
54 or manganese 52 and whole-body retention measurements. The fractional
manganese absorption from human milk (8.2% +/- 2.9%) was significantly
different when compared with cow's milk (2.4% +/- 1.7%), soy formula (0.7%
+/- 0.2%), and whey-preponderant cow's milk formula with 12 mg/L of iron
(1.7% +/- 1.0%) and without iron fortification (2 mg/L of iron) (3.1% +/-
2.8%), while no significant difference was observed between a
whey-preponderant cow's milk formula with 7 mg/L of iron (5.9% +/- 4.8%)
and human milk. The total amount of absorbed manganese was significantly
higher from the non--iron-fortified cow's milk formula (2 mg/L of iron) as
compared with human milk, while no significant differences were observed
for the other milks and formulas.
