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Treatment of the Young Child With Postoperative Central Diabetes Insipidus
Jay A. McDonald, MD;
Paul M. Martha, Jr, MD;
James Kerrigan, MD;
William L. Clarke, MD;
Alan D. Rogol, MD, PhD;
Robert M. Blizzard, MD
Am J Dis Child. 1989;143(2):201-204.
Abstract
• A continuous intravenous infusion of aqueous vasopressin (dosage range, 1.0 to 3.0 mU/kg/h) was administered to two patients (respective ages, 2 weeks and 3 years 1 month) who had postoperative central diabetes insipidus to determine if this mode of therapy is helpful in the very young patient. In both patients the polyuria and serum hyperosmolality were corrected. These findings suggest that an intravenous infusion of aqueous vasopressin can provide satisfactory control of the polyuria and electrolyte disturbances found in young children with acute postoperative central diabetes insipidus.
(AJDC 1989;143:201-204)
Author Affiliations
From the Department of Pediatrics, University of Virginia School of Medicine, Charlottesville.
Footnotes
Accepted for publication Nov 17, 1988.
Reprint requests to Division of Endocrinology, Department of Pediatrics, Box 386, University of Virginia School of Medicine, Charlottesville, VA 22908 (Dr McDonald).
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