This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Relationship to Gonadotropin Excretion

Howard E. Kuhn, MD; Miguel A. Frontera, MD; Laurence M. Demers, PhD; Mary J. Bartholomew, MS; Thomas A. Lloyd, PhD

Am J Dis Child. 1989;143(2):190-193.

Abstract
• To determine the relationship of gonadotropin excretion to spermarche, 26 boys ranging in age from 10.3 to 17.5 years each provided ten overnight urine samples. Microscopic observation of sperm was found in 33 (13%) of the 260 samples, with 50% of the boys exhibiting sperm in at least one specimen. No further cumulative gain in detecting spermaturia occurred after the seventh urine collection. The median age of spermarche was computed by logistic regression analysis to be 14 years. Three urine collections from each boy were assessed for gonadotropin levels. At age 14 years mean follicule-stimulating hormone and luteinizing hormone excretion were, respectively, 857 and 503 mlU/h, into the reported adult daytime range. Spermarche is a midpubertal event associated with age-appropriate gonadotropin production.

(AJDC 1989;143:190-193)

Author Affiliations
From the Department of Pediatrics, Division of Pediatric Endocrinology (Drs Kulin and Frontera), Department of Pathology, Core Endocrine Laboratory (Dr Demers), the Center for Biostatistics and Epidemiology (Ms Bartholomew), and the Department of Obstetrics/Gynecology, Division of Reproductive Endocrinology (Dr Lloyd), Milton S. Hershey Medical Center, The Pennsylvania State University, Hershey.

Footnotes
Accepted for publication Nov 9, 1988.

Reprint requests to Department of Pediatrics, Division of Endocrinology, Milton S. Hershey Medical Center, PO Box 850, Hershey, PA 17033 (Dr Kulin).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Preservation of Fertility in Pediatric and Adolescent Patients With Cancer
Fallat et al.
Pediatrics 2008;121:e1461-e1469.
ABSTRACT | FULL TEXT  

Cryopreservation of Sperm From Adolescents and Adults With Malignancies
Kamischke et al.
J Androl 2004;25:586-592.
ABSTRACT | FULL TEXT  

Personal practice: Fertility preservation for children treated for cancer (1): scientific advances and research dilemmas
Grundy et al.
Arch. Dis. Child. 2001;84:355-359.
FULL TEXT  

Testicular tissue cryopreservation in boys. Ethical and legal issues: Case report
Bahadur et al.
Hum Reprod 2000;15:1416-1420.
ABSTRACT | FULL TEXT  

Gonadal tissue cryopreservation in boys with paediatric cancers
Bahadur and Ralph
Hum Reprod 1999;14:11-17.
ABSTRACT | FULL TEXT  

Sex Steroid Treatment of Constitutionally Tall Stature
Drop et al.
Endocr. Rev. 1998;19:540-558.
ABSTRACT | FULL TEXT