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Alberto S. Pappo, MD; George R. Buchanan, MD; Andrea Johnson, MSN, PNP

Am J Dis Child. 1989;143(10):1226-1228.

Abstract
• Four of the 139 children with hemophilia followed up at our center have developed septic arthritis during the past 6 years (2.9% incidence). Two infections were caused by Streptococcus pneumoniae and one each by staphylococcus aureus and Haemophilus influenzae type B. Common features at time of presentation included fever and a 2- to 7-day history of joint pain and swelling unresponsive to factor replacement infusions. Since three of the patients were human immunodeficiency virus seropositive, we propose that human immunodeficiency virus infection may be responsible for the disproportionately high number of cases of septic arthritis observed in our patient population.

(AJDC. 1989;143:1226-1228)

Author Affiliations
From the Department of Pediatrics, the North Texas Comprehensive Hemophilia Center, the University of Texas Southwestern Medical Center at Dallas; and Children's Medical Center, Dallas.

Footnotes
Accepted for publication May 1, 1989.

Reprint requests to Department of Pediatrics, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75235-9063 (Dr Buchanan).

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