Sublingual lorazepam in childhood serial seizures
J. Y. Yager and S. S. Seshia
Section of Pediatric Neurosciences, Children's Hospital of Winnipeg, Manitoba, Canada.
Sublingual lorazepam was successful in controlling serial seizures in ten
children. There was both intrasubject and intersubject variability in the
effective dose, which ranged from about 0.05 mg/kg to 0.15 mg/kg. Side
effects were minimal and consisted of drowsiness, unsteadiness, nausea, and
hyperactivity. Sublingual lorazepam is an easy and effective way to treat
serial seizures at home.
