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Yvonne E. Vaucher, MD; T. Allen Merritt, MD; Mikko Hallman, MD; Anna-Liisa Jarvenpaa, MD; Aimee M. Telsey, MD; Barbara L. Jones, RN, MN, CPNP

Am J Dis Child. 1988;142(9):927-930.

Abstract
• We assessed postnatal growth, neurodevelopmental outcome, and occurrence of respiratory illnesses In 46 infants of very low birth weight who were enrolled in a randomized, controlled, bicenter clinical trial of human surfactant treatment for respiratory distress syndrome. No long-term adverse effects of human surfactant treatment were detected between control and human surfactant–treated infants with respect to growth, neurologic, or developmental outcome. Infants with chronic lung disease, regardless of treatment group, had poorer growth and were more likely to have neurodevelopmental abnormalities at 12 to 24 months of age.

(AJDC 1988;142:927-930)

Author Affiliations
From the Divisions of Neonatology, Departments of Pediatrics, University of California-San Diego (Drs Vaucher, Merritt, and Telsey and Ms Jones), and University of Helsinki (Drs Hallman and Jarvenpaa).

Footnotes
Accepted for publication June 2, 1988.

Reprint requests to UCSD Medical Center, H-814-J, Department of Pediatrics, Division of Neonatology, 225 W Dickinson, San Diego, CA 92103 (Dr Vaucher).

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