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Ribavirin Administration to Infants Receiving Mechanical Ventilation
Kristan M. Outwater, MD;
H. Cody Meissner, MD;
Myron B. Peterson, MD, PhD
Am J Dis Child. 1988;142(5):512-515.
Abstract
• Aerosolized ribavirin was administered to 12 infants with bronchiolitis who were receiving mechanical ventilation. All patients had a history of cardiac or pulmonary disease and developed severe respiratory failure during their infection. We developed a method for ribavirin administration and patient monitoring that included timed circuit valve and tubing changes to avoid obstruction by precipitated drug, frequent endotracheal tube suctioning, and constant observation of the patient and ventilator. All patients were successfully treated. We conclude that ribavirin can be safely administered to infants receiving mechanical ventilation.
(AJDC 1988;142:512-515)
Author Affiliations
From the Department of Pediatrics, Divisions of Critical Care (Drs Outwater and Peterson) and Infectious Diseases (Dr Meissner), and The Floating Hospital for Infants and Children, New England Medical Center, Boston.
Footnotes
Accepted for publication Jan 21, 1988.
Reprint requests to the Pediatric Critical Care Services, New England Medical Center Hospitals, Box 93, 750 Washington St, Boston, MA 02111 (Dr Outwater).
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