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A Pilot Study

Richard Famularo, MD; Robert Kinscherff, PhD; Terence Fenton, EdD

Am J Dis Child. 1988;142(11):1244-1247.

Abstract
• We report 11 cases of posttraumatic stress disorder. Each child had been physically abused or sexually abused or both and presented in an agitated, hyperaroused state. Using a B-A-B (off-on-off) medication design in a clinical setting, the children were treated with the beta-adrenergic antagonist propranolol. Scores on an inventory of symptoms of posttraumatic stress disorder indicated that patients exhibited significantly fewer symptoms while receiving medication than either before or after they received medication.

(AJDC 1988;142:1244-1247)

Author Affiliations
From the Department of Psychiatry, Harvard Medical School (Dr Famularo); the Department of Psychiatry, The Children's Hospital (Drs Famularo and Kinscherff); Boston Juvenile Court (Drs Famularo and Kinscherff); and the Department of Biostatistics, School of Public Health, Harvard University (Dr Fenton), Boston.

Footnotes
Accepted for publication July 10, 1988.

Reprints not available.

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References
APPI Online CME 2007;2007:2-2.
FULL TEXT  

Elevations of Serum T3 Levels and Their Association With Symptoms in World War II Veterans With Combat-Related Posttraumatic Stress Disorder: Replication of Findings in Vietnam Combat Veterans
Wang and Mason
Psychosom. Med. 1999;61:131-138.
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