Typhoid and paratyphoid fever in 192 hospitalized children in Thailand
U. Thisyakorn, P. Mansuwan and D. N. Taylor
From 1977 to 1984, Salmonella typhi was isolated from 85% and Salmonella
paratyphl A was isolated from 15% of 192 Thai children with enteric fever
at Children's Hospital, Bangkok. Children with enteric fever presented with
sudden onset of fever and gastrointestinal symptoms. of fever presented
with sudden onset Diarrhea occurred in 62% of children with paratyphoid
fever and 36% of children with typhoid fever. Rose spots were seen in 15%
of patients with typhoid and 7% of patients with paratyphoid fever. There
were no deaths. Bronchitis and pneumonia occurring in 11% of patients were
the most common complications. Acute hemolysis occurred in 3% of the
patients with typhoid fever who had thalassemia or glucose-6-phosphate
dehydrogenase deficiency. Chloramphenicol-resistant S typhi, which
accounted for 70% of the isolates in 1977, has since 1982 accounted for
less than 2% of isolates.