This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

William P. Kanto, Jr, MD; Rickey Wilson, MD; Gerard L. Breart, MD; Sally Zierler, DPH; Dilip M. Purohit, MD; George J. Peckham, MD; R. Curtis Ellison, MD

Am J Dis Child. 1987;141(2):167-169.

Abstract
• Among 2123 premature infants monitored during a large multicenter study of patent ductus arteriosus, necrotizing enterocolitis (NEC) was diagnosed in 121 (5.7%) of these infants. Rates ranged from 13.5% among infants with a birth-weight (BW) of 500 to 749 g to 2.9% among infants whose BW was between 1500 and 1750 g. The presence of a hemodynamically significant patent ductus arteriosus did not alter the incidence of NEC. Of a large number of perinatal events and conditions considered, only BW and maternal toxemia were found to be associated with the rate of NEC, both relating inversely. Thus, these data do not support a relationship between NEC and a variety of perinatal factors previously postulated as potential determinants of the disorder.

(AJDC 1987;141:167-169)

Author Affiliations
From the Department of Pediatrics, Medical College of Georgia, Atlanta (Dr Kanto); Section on Clinical Drug Safety, Boehringer Ingelheim Pharmaceutical Inc, Ridgefield, Conn (Dr Wilson); Department of Epidemiology, National Institute of Health and Medical Research Group, Paris (Dr Breart); Department of Community Health, Brown University, Providence, RI (Dr Zierler); Department of Pediatrics, Medical University of South Carolina, Charleston (Dr Purohit); Section of Perinatal Pediatrics, Children's Hospital of Philadelphia (Dr Peckham); and Department of General Medicine and Primary Care, University of Massachusetts, Worcester (Dr Ellison).

Footnotes
Accepted for publication Sept 9, 1986.

Reprint requests to Department of Pediatrics, Medical College of Georgia, Augusta, GA 30912 (Dr Kanto).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Effects of a Patent Ductus Arteriosus on Postprandial Mesenteric Perfusion in Premature Baboons
McCurnin and Clyman
Pediatrics 2008;122:e1262-e1267.
ABSTRACT | FULL TEXT  

Growth of Very Premature Infants Fed Intravenous Hyperalimentation and Calcium-supplemented Formula
Berry et al.
Pediatrics 1997;100:647-653.
ABSTRACT | FULL TEXT  

Feeding Premature Infants
Robertson and Bhatia
CLIN PEDIATR 1993;32:36-44.