An analysis of 248 initial mobilization tests performed on an ambulatory basis
H. L. Weinberger, E. M. Post, T. Schneider, B. Helu and J. Friedman
Department of Pediatrics, State University of New York Health Science Center, Syracuse 13210.
Data are presented on 248 initial mobilization tests performed in an
ambulatory setting over an 11-year period. Results demonstrate that there
is no single, consistent predictor of body burden of lead, although the
higher the blood lead level, the greater the amount of excretable
(mobilizable) lead. It is recommended that an appropriate ratio of lead
excreted in response to chelant is equal to or greater than 0.5 based on
this series of tests. A recommendation is also made to realign the Centers
for Disease Control (Atlanta) guidelines for classification of risk. This
realignment would coincide with a recommendation that mobilization tests be
reserved for children whose blood lead levels ranged from 1.93 to 2.57
mumol/L (40 to 60 micrograms/dL). Those with higher levels would undergo
chelation without prior mobilization studies.