Antidiuretic hormone excess in infant botulism
G. Kurland and J. Seltzer
Department of Pediatrics, University of California, Davis, School of Medicine.
Two infants developed evidence of antidiuretic hormone excess as a
complication of infant botulism. Neither child received mechanical
ventilatory support before the development of hyponatremia, serum
hyposmolality, and urinary hyperosmolality. Both infants responded to
fluid-intake restriction. The appearance of hyponatremia in an infant with
botulism should suggest antidiuretic hormone excess. The recognition of
this entity will lead to its appropriate management with fluid-intake
restriction.
