Sweet's syndrome with multifocal sterile osteomyelitis
T. C. Edwards, F. B. Stapleton, M. J. Bond and F. F. Barrett
Sweet's syndrome is a rare condition characterized by fever, leukocytosis,
dense dermal infiltration of leukocytes, and painful indurated cutaneous
plaques. We describe a 23-month-old male infant with the typical cutaneous
manifestations of Sweet's syndrome and painful extremities that limited
ambulation. Evaluation revealed multifocal sterile osteomyelitis of both
tibia. After the institution of systemic corticosteroid therapy, the
patient's symptoms resolved, and bone scans normalized. After one year of
follow-up, the patient has intermittent recrudescences that resolve during
corticosteroid therapy. Sterile multifocal osteomyelitis represents another
clinical manifestation of Sweet's syndrome.
