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Erawati V. Bawle, MD; Virginia Black, MD

Am J Dis Child. 1986;140(8):758-760.

Abstract
• Nonimmune hydrops fetalis has been reported to be associated with congenital malformations. We describe two newborns with Noonan's syndrome who presented with nonimmune hydrops fetalis that was most likely secondary to a generalized lymphatic vessel dysplasia. Other manifestations of lymphatic abnormalities in Noonan's syndrome, such as pedal edema and pulmonary and intestinal lymphangiectasis, have been observed in children. Non-immune hydrops represents one end of the spectrum of abnormalities seen in this syndrome.

(AJDC 1986;140:758-760)

Author Affiliations
From the Department of Pediatrics, Wayne State University, Detroit (Drs Bawle and Black); the Divisions of Genetic, Metabolic, and Developmental Disorders (Dr Bawle) and Neonatology (Dr Black), Children's Hospital of Michigan, Detroit; and the Division of Neonatology, Hutzel Hospital, Detroit (Dr Black).

Footnotes
Accepted for publication Jan 20, 1986.

Reprint requests to Children's Hospital of Michigan, 3901 Beaubien, Detroit, MI 48201 (Dr Bawle).

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