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Angela W. Miser, MBBS; Karen J. Chayt, MD; John T. Sandlund, MD; Pamela S. Cohen, MD; Judith A. Dothage, RN; James S. Miser, MD

Am J Dis Child. 1986;140(6):603-604.

Abstract
• Five young adults with malignant neoplasms developed symptoms of narcotic withdrawal six to 48 hours after the abrupt discontinuation of narcotic therapy that had been administered for six to 21 days. The symptoms, which included agitation, irritability, muscular jerks, abdominal pain, diarrhea, burning sensations, "gooseflesh," and itching, rapidly resolved when narcotic therapy was reinstituted. Four patients were then successfully weaned from opiates without recurrence of their withdrawal symptoms; the fifth patient continues to receive methadone hydrochloride treatment for continuing pain.

(AJDC 1986;140:603-604)

Author Affiliations
From the Pediatric Branch, National Cancer Institute, National Institutes of Health, Bethesda, Md.

Footnotes
Accepted for publication Feb 9, 1986.

Reprint requests to Pediatric Branch, National Cancer Institute, National Institutes of Health, Bldg 10, Room 13N240, Bethesda, MD 20892 (Dr Miser).

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