Perinatal factors and periventricular-intraventricular hemorrhage in preterm infants
M. Van de Bor, F. Van Bel, R. Lineman and J. H. Ruys
We studied 49 consecutively admitted infants of less than 34 weeks'
gestation to analyze the role of several maternal, intrapartum, and
neonatal factors associated with the occurrence of
periventricular-intraventricular hemorrhage (PIVH). To detect PIVH,
ultrasound studies were performed every eight hours during the first three
days of life and every 12 hours during the following four days. In 20
infants (41%) PIVH was detected. Of these 20 cases, 30% were diagnosed
immediately after birth and 55%, 70%, 90%, and 100% after 24, 48, 72, and
108 hours, respectively. Hypoxia, hypercapnia, and acidosis were the most
important factors associated with the development of PIVH. Hypothermia was
also an antecedent. Suctioning, serum osmolality, weight loss,
transfusions, pneumothorax, patent ductus arteriosus, and bolus infusions
with sodium bicarbonate were not associated with the onset of PIVH.
