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Serologic Evidence

H. Robert Harrison, DPhil, MD, MPH; Laurence S. Magder, MPH; W. Thomas Boyce, MD; Joanne Hauler, MPA; Thomas M. Becker, MD; John A. Stewart, MD; Dorreth D. Humphrey, MS

Am J Dis Child. 1986;140(10):1068-1071.

Abstract
• Serum samples from 184 Infants and children whose blood was drawn during a clinic visit were tested for antibody to Chlamydia trachomatis, Epstein-Barr virus, and cytomegalovirus. Lifetime illness history was obtained from clinic records. Fifteen percent had anti–C trachomatis IgM antibody. Anti–C trachomatis IgM without IgG was significantly associated with upper respiratory tract syndromes within the 14 days prior to phlebotomy in 6- to 10-year-old patients. This association was not due to polyclonal activation from Epstein-Barr virus infection. A definitive study of chlamydial illness in children rather than infants appears to be indicated.

(AJDC 1986;140:1068-1071)

Author Affiliations
From the Division of Sexually Transmitted Diseases, Center for Prevention Services (Drs Harrison and Becker and Mr Magder), and the Viral Diseases Division, Center for Infectious Diseases (Dr Stewart and Ms Humphrey), Centers for Disease Control, Atlanta; the Department of Pediatrics, University of Arizona School of Medicine, Tucson (Dr Boyce); and the Crown-point (NM) Indian Health Service Hospital (Ms Hauler).

Footnotes
Accepted for publication June 23, 1986.

Reprint requests to Technical Information Services, Division of Sexually Transmitted Diseases, Centers for Disease Control, Atlanta, GA 30333 (Dr Harrison).

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