Effects of maturation and gastric acidity on gastroesophageal reflux in infants
J. L. Sutphen and V. L. Dillard
Using prolonged esophageal pH monitoring, we examined 42 infants referred
for gastroesophageal reflux (GER) over a 16-month interval. Eighteen of
these infants were also examined with intragastric pH monitoring following
a standard formula meal. We found that prematurity and postcibal gastric
acidity were significantly correlated with the amount of GER observed.
Historical symptoms appeared to have little correlation with the amount of
GER as measured by prolonged intraesophageal pH monitoring.