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Lorazepam in the Treatment of Refractory Neonatal SeizuresA Pilot Study
Anita Deshmukh, MD;
William Wittert, MD;
Eugene Schnitzler, MD;
Henry H. Mangurten, MD
Am J Dis Child. 1986;140(10):1042-1044.
Abstract
Seven neonatal patients with severe seizures unresponsive to conventional anticonvulsant therapy were treated with lorazepam. Immediate cessation of seizure activity occurred in all patients within five minutes. Although seizures recurred in two infants eight hours later, frequency and severity diminished. There were no apparent significant side effects attributed to the medication.
(AJDC 1986;140:1042-1044)
Author Affiliations
From the Division of Pediatrics (Dr Wittert), Sections of Pediatric Neurology (Dr Schnitzler) and Neonatology (Drs Deshmukh and Mangurten), Lutheran General Hospital, Park Ridge, Ill.
Footnotes
Accepted for publication June 16, 1986.
Reprint requests to Neonatology Office, Lutheran General Hospital, 1775 W Dempster St, Park Ridge, IL 60068 (Dr Mangurten).
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