Lorazepam in the treatment of refractory neonatal seizures. A pilot study
A. Deshmukh, W. Wittert, E. Schnitzler and H. H. Mangurten
Seven neonatal patients with severe seizures unresponsive to conventional
anticonvulsant therapy were treated with lorazepam. Immediate cessation of
seizure activity occurred in all patients within five minutes. Although
seizures recurred in two infants eight hours later, frequency and severity
diminished. There were no apparent significant side effects attributed to
the medication.