This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Zeev Hochberg, MD; Jakob Schechter, MD; Abraham Benderly, MD; Esther Leiberman, MD; Ariel Rosler, MD

Am J Dis Child. 1985;139(8):771-776.

Abstract
• To evaluate growth and pubertal development in patients with congenital adrenal hyperplasia due to 11-β-hydroxylase deficiency, data were collected retrospectively from the charts of 24 patients, 15 girls and nine boys. Growth before diagnosis was characterized by a rapid acceleration in the second half of the first year of life, with rapid advancement of bone age. Final height was severely compromised in all the patients, regardless of age at diagnosis and quality of therapeutic control. Onset of puberty was precocious in male patients and normal in female patients. In this respect, treatment with hydrocortisone acetate proved to be superior to cortisone acetate or prednisone.

(AJDC 1985;139:771-776)

Author Affiliations
From the Departments of Pediatrics, Rambam Medical Center and Faculty of Medicine, Technion–Israel Institute of Technology, Haifa (Drs Hochberg and Benderly), Haifa (Israel) Medical Center (Drs Hochberg and Schechter), Soroka Medical Center, Beersheeba, Israel (Dr Leiberman), and Hebrew University–Hadassah Medical Center, Jerusalem (Dr Rosler).

Footnotes
Reprint requests to Endocrine Laboratory, Rambam Medical Center, PO Box 9602, Haifa 31096, Israel (Dr Hochberg).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Mutations in CYP11B1 and Congenital Adrenal Hyperplasia in Moroccan Jews
Paperna et al.
J. Clin. Endocrinol. Metab. 2005;90:5463-5465.
ABSTRACT | FULL TEXT  

Estradiol Stimulation of Pulsatile Gonadotropin-Releasing Hormone Secretion in Vitro: Correlation with Perinatal Exposure to Sex Steroids and Induction of Sexual Precocity in Vivo
Matagne et al.
Endocrinology 2004;145:2775-2783.
ABSTRACT | FULL TEXT  

The Timing of Normal Puberty and the Age Limits of Sexual Precocity: Variations around the World, Secular Trends, and Changes after Migration
Parent et al.
Endocr. Rev. 2003;24:668-693.
ABSTRACT | FULL TEXT