Chronic T-cell lymphocytosis with neutropenia. Its association with Epstein-Barr virus infection
H. G. Herrod, W. C. Wang and J. L. Sullivan
Chronic T-cell lymphocytosis with neutropenia has primarily been reported
in adults. We have cared for a 14-year-old patient with this condition for
over five years. This patient consistently had greater than 90% lymphocytes
in his differential cell count. The majority of these cells had the OKT8
phenotype. Serologic studies demonstrated evidence for a chronic
Epstein-Barr infection with elevated antibody titers to both early antigen
and to the viral capsid antigen. Patients presenting with this condition
should be carefully evaluated for possible viral infection.
