Slipped capital femoral epiphysis in growth hormone-deficient patients
E. B. Rappaport and D. Fife
Slipped capital femoral epiphysis (SCFE), a potentially disabling hip
disorder, occurs primarily during the pubertal growth spurt. It has been
reported in association with pituitary gigantism, growth hormone
deficiency, hypothyroidism, hypogonadism, and panhypopituitarism. We
estimated the frequency of SCFE among children with growth hormone
deficiency (treated or untreated) and compared it with the reported
frequency of SCFE among Connecticut residents under 25 years of age. Based
on this comparison, the risk of developing SCFE is significantly greater in
growth hormone-deficient children than in the general population.
