Psychosis and seizures following the injection of penicillin G procaine. Hoigne's syndrome
T. J. Silber and L. D'Angelo
Psychosis and/or seizures following the administration of intramuscular
penicillin G procaine have not been reported in the pediatric literature to
our knowledge. This omission is regrettable in light of the frequency with
which this treatment is indicated as therapy for gonococcal infections. We
report clinical data from four patients afflicted by this reaction known as
Hoigne's syndrome. The dramatic and unexpected manifestation of this
condition calls for an immediate diagnosis to proceed with the appropriate
treatment.
