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Protein Quality and Quantity in Preterm Infants Receiving the Same Energy Intake
Pauline Darling;
Guy Lepage;
Patrick Tremblay;
Sylvie Collet, RN;
Larry C. Kien, MD;
Claude C. Roy, MD
Am J Dis Child. 1985;139(2):186-190.
Abstract
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Fifteen low-birth-weight appropriate for gestational age infants, weighing 1.3 to 1.6 kg, were assigned to three isocaloric formulas differing in the quantity and form of nitrogen delivered. A balance study was done between 21 and 30 days after birth. Nitrogen retention expressed as milligram per kilogram per 100 kcal of metabolizable energy was greater with the 60:40 whey/casein and with the casein hydrolysate preparations than with the 20:80 whey/casein formula, which provided the same amount of energy (150 kcal/kg/day) but smaller quantities of protein (3.5 g/kg/day) than the two others (4.3 g/kg/day and 4.4 g/kg/day). Weight gain until discharge from the hospital and increment of height and head circumference over a three-month period showed an advantage of the two formulas providing higher intakes of protein. This study suggests that with high-energy intakes, protein quality does not affect nitrogen retention and growth unless the quantity of protein ingested falls below a critical level.
(AJDC 1985;139:186-190)
Author Affiliations
From the Hôpital Ste-Justine, Montreal (Mss Darling and Collet, Messrs Lepage and Tremblay, and Dr Roy); the Milwaukee Children's Hospital (Dr Kien); and the Departments of Pediatrics, the University of Montreal (Mss Darling and Collet, Messrs Lepage and Tremblay, and Dr Roy) and the Medical College of Wisconsin, Milwaukee (Dr Kien).
Footnotes
Reprint requests to Pediatric Research Center, Hôpital Ste-Justine, 3175, Ste-Catherine Rd, Montreal, Quebec, Canada H3T IC5 (Dr Roy).
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