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Increased Efficacy of Technetium Tc 99m Succimer in Screening for Renal Disease

Paul R. Rosen, MD; S. Treves, MD; Julie Ingelfinger, MD

Am J Dis Child. 1985;139(2):173-177.

Abstract
• Renal scintigraphy with technetium Tc 99m succimer (DMSA) and technetium Tc 99m pentetate (DTPA) was used to study 80 hypertensive pediatric and adolescent patients. Renal abnormalities such as asymmetry of function, size, or shape were identified in 13 patients. Both excretory urography and technetium Tc 99m pentetate studies were successful in detecting 54% of the abnormalities in patients studied; technetium Tc 99m succimer identified 92%. The accuracy of the latter was 96%, with a specificity of 97%. The ability of technetium Tc 99m succimer renal scintigraphy to identify accurately the presence or absence of renal abnormalities warrants its inclusion in the initial examination of pediatric and adolescent patients with hypertension.

(AJDC 1985;139:173-177)

Author Affiliations
From the Department of Radiology/Nuclear Medicine, The Children's Hospital (Drs Rosen and Treves), and the Department of Medicine, Harvard Medical School (Dr Ingelfinger), Boston.

Footnotes
Reprint requests to Division of Nuclear Medicine, The Children's Hospital, 300 Longwood Ave, Boston, MA 02115 (Dr Rosen).

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