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A Prospective Study

CPT Richard Meidell, MC, USA; LTC Philip Marinelli, MC, USA; LTC Gary Pettett, MC, USA

Am J Dis Child. 1985;139(2):160-163.

Abstract
• Serial ultrasound examinations were performed on 40 consecutive newborn infants less than 35 weeks' gestational age. Fifteen of 17 infants with intracranial hemorrhage (ICH) had evidence of hemorrhage on the first ultrasound examination (mean age, 1.9± 0.2 hours post partum). Comparing the clinical course of these 15 infants with age- and weight-matched nonhemorrhage controls showed a significant association between the occurrence of early ICH and the pattern of labor. There was no correlation between ICH and the mode of delivery, the use of sodium bicarbonate, volume administration, or the initial BP. In nine of the 15 infants with early-onset ICH, the hemorrhage progressed in severity during the first three postpartum days in association with increasing ventilatory requirements. The results of this study suggest that the course of labor may be a precipitating factor In the onset and evolution of early ICH.

(AJDC 1985;139:160-163)

Author Affiliations
From the Newborn Medicine Service, Department of Pediatrics, Madigan Army Medical Center, Tacoma, Wash.

Footnotes
Read in part before the annual fall meeting of the American Academy of Pediatrics, New York, Oct 26, 1982.

The opinions and assertions herein contained are those of the authors and do not necessarily represent those of the Department of Defense or the Department of the Army.

Reprint requests to Newborn Medicine Service, Box 845, Madigan Army Medical Center, Tacoma, WA 98431 (LTC Pettett).

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