Measles reimmunization in children immunized before 1 year of age
R. M. Lampe, M. R. Weir, R. M. Scott and J. L. Weeks
An outbreak of measles presented an opportunity to examine the immune
response of children initially immunized with measles vaccine before 1 year
of age to reimmunization at 15 months of age with measles, mumps, and
rubella vaccine. Eighteen previously immunized children had higher acute
and convalescent hemagglutination inhibition titers than 13 control
children. None of the previously immunized children had measles-specific
IgM appear in convalescent serum samples. These results indicate a brisk
secondary immune response to measles reimmunization in children immunized
before 1 year of age. They support the recommendation of the American
Academy of Pediatrics of reimmunization at 15 months of age for those
children whose initial measles immunization was before 1 year of age.
