Bone mineral status in childhood accidental fractures

G. M. Chan, M. Hess, J. Hollis and L. S. Book

We studied the bone mineral and calcium (Ca) status of 17 children who suffered an accidental fracture in 1980. These children were matched by age and sex to a nonfractured control group. Blood was drawn for serum Ca, phosphorus, magnesium, 25-hydroxycholecalciferol ( calcidiol ), alkaline phosphatase, and albumin. Bone mineral content (BMC) was evaluated by photon absorptiometry. There were no differences in serum values between the two groups. Twelve (71%) of the 17 children in the fracture group had a lower BMC than their matched controls. The BMC of the fracture group was lower than their controls, 0.423 +/- 0.042 v 0.461 +/- 0.037 g/cm. Four of the 15 in the fracture group ingested less than 60% of the recommended dietary allowance (RDA) for Ca and P (800 mg/day), while all the controls were ingesting at least 60% of the RDA. Four children of the fracture group who were ingesting less Ca and P than those of the control group also had low BMC.

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Pubertal Timing, Peak Bone Mass and Fragility Fracture Risk
Bonjour and Chevalley
IBMS BoneKEy 2007;4:30-48.
ABSTRACT | FULL TEXT  

Association Between Bone Density and Fractures in Children: A Systematic Review and Meta-analysis
Clark et al.
Pediatrics 2006;117:e291-e297.
ABSTRACT | FULL TEXT  

Bone mass acquisition in healthy children
Davies et al.
Arch. Dis. Child. 2005;90:373-378.
ABSTRACT | FULL TEXT  

Calcium supplementation and bone mineral density in females from childhood to young adulthood: a randomized controlled trial
Matkovic et al.
Am. J. Clin. Nutr. 2005;81:175-188.
ABSTRACT | FULL TEXT  

Bone density at the os calcis: reference values, reproducibility, and effects of fracture history and physical activity
Chinn et al.
Arch. Dis. Child. 2005;90:30-35.
ABSTRACT | FULL TEXT  

The Association between Bone Mineral Density, Metacarpal Morphometry, and Upper Limb Fractures in Children: A Population-Based Case-Control Study
Ma and Jones
J. Clin. Endocrinol. Metab. 2003;88:1486-1491.
ABSTRACT | FULL TEXT  

Hormonal Determinants and Disorders of Peak Bone Mass in Children
Soyka et al.
J. Clin. Endocrinol. Metab. 2000;85:3951-3963.
FULL TEXT  

Bone Mineral Density in Children With Myelomeningocele
Quan et al.
Pediatrics 1998;102:e34-e34.
ABSTRACT | FULL TEXT