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Incidence and Outcome in a Population of Very-Low-Birth-Weight Infants

Sam Hawgood, MB, FRACP; Joan Spong, MB, DDU, FRCR, MRACR; Victor Y. H. Yu, MD, MSc, MRCP, FRACP

Am J Dis Child. 1984;138(2):136-139.

Abstract
• The incidence, extent, and outcome of germinal matrix hemorrhage-intraventricular hemorrhage (GMH-IVH) were determined with the use of ultrasound and autopsy findings in 100 consecutive infants, with a birth weight of less than 1,500 g. Serial ultrasound examinations once or twice weekly were performed with the use of a portable real-time linear-array scanner. The overall incidence of GMH-IVH was 46%. Twenty infants had grade 1 (GMH), 24 had grade 2 (IVH ± GMH), and two had grade 3 (IVH±GMH with intracerebral hemorrhage) conditions. The mortality in infants with GMH-IVH was 35%, compared with 13% in infants without GMH-IVH. Although 11 (37%) of 30 survivors with GMH-IVH had ventricular dilatation, only two infants required ventriculoperitoneal shunts for progressive hydrocephalus. The incidence of GMH-IVH was increased in outborn infants, in those delivered vaginally, and in those who required mechanical ventilation, bicarbonate therapy, or volume expansion in the first 24 hours. The long-term prognostic significance of the ultrasound findings was unknown and will be determined by follow-up studies.

(AJDC 1984;138:136-139)

Author Affiliations
From the Departments of Pediatrics (Drs Hawgood and Yu) and Radiology (Dr Spong), Queen Victoria Medical Centre, Melbourne.

Footnotes
Reprint requests to Department of Pediatrics, Queen Victoria Medical Centre, 172 Lonsdale St, Melbourne, Victoria 3000, Australia (Dr Yu).

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