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Scott H. Isaacman, MD; William M. Heroman, MD; Alton L. Lightsey, MD

Am J Dis Child. 1984;138(10):915-916.

Abstract
• A 16-day-old male infant initially was in septic shock. Following intensive resuscitation, thrombohemorrhagic lesions developed over his extremities, except for the limb with an arterial line maintained by a continuous heparin sodium infusion. Blood and CSF cultures yielded group B β-hemolytic streptococci. Results of laboratory studies and clinical appearance supported the diagnosis of purpura fulminans (PF). Systemic heparinization was therefore started, and subsequently his condition improved. Because of the distinct difference in limb sparing, we concluded heparin has a beneficial effect on the evolution of PF.

(AJDC 1984;138:915-916)

Author Affiliations
From the Department of Pediatrics (Dr Isaacman), Divisions of Neonatology (Dr Heroman) and Hematology-Oncology (Dr Lightsey) and the Clinical Investigation Department, Naval Hospital, San Diego.

Footnotes
The opinions or assertions contained herein are those of the authors and are not to be construed as official or as necessarily reflecting the views of the Department of the Navy or the naval service at large.

Reprint requests to Clinical Investigation Department, Naval Hospital, San Diego, CA 92134 (Dr Isaacman).

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ABSTRACT