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Role of Breast-feeding and Other Causes

M. Jeffrey Maisels, MB, BCh; Kathleen Gifford, RNC

Am J Dis Child. 1983;137(6):561-562.

Abstract
• Serum bilirubin determinations were performed on 264 term infants who were consecutively delivered via the vaginal route. Forty-one infants (15.5%) had serum bilirubin concentrations greater than 12 mg/dL. No cause for this was found, initially, in 23 (56%) of these infants. On the third hospital day, the mean (±SD) serum bilirubin level was 6.9±3.6 mg/dL in breast-fed infants and 6.5±3.2 mg/dL in bottle-fed infants. Of the 23 infants without obvious cause for hyperbilirubinemia, eight (four bottle-fed and four breast-fed infants) had serum bilirubin concentrations greater than 12 mg/dL on the third hospital day, whereas in 15(14 breast-fed infants and one bottle-fed infant), the elevated serum bilirubin level occurred on day 4 or 5. Breast-feeding does not seem to affect the total serum bilirubin level in the first three days of life but may be associated with an increased incidence of hyperbilirubinemia subsequently. In a normal full-term population, routine investigations do not disclose a cause for hyperbilirubinemia in about half of the patients.

(Am J Dis Child 1983;137:561-562)

Author Affiliations
From the Division of Newborn Medicine, Department of Pediatrics, The Milton S. Hershey Medical Center, Pennsylvania State University, Hershey.

Footnotes
Reprint requests to Department of Pediatrics, The Milton S. Hershey Medical Center, Hershey, PA 17033 (Dr Maisels).

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