This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

C. Murry Thompson, Jr, MD; Peter H. Gilligan, PhD; Margaret C. Fisher, MD; Sarah S. Long, MD

Am J Dis Child. 1983;137(3):271-274.

Abstract
• Assays for cytotoxin of Clostridium difficile were performed on stool samples submitted to the laboratory for routine microbiologic study. Cytotoxin was recovered from 8.6% of 208 pediatric patients studied. Cytotoxin was identified significantly more often in younger patients (median age, 11 months) and in those with hospital-associated illness (17%) and antibiotic-associated illness (18%). Hospitalization and antibiotic use were significant independent risk factors. Clinical diagnoses in patients with C difficile cytotoxin included classic pseudomembranous colitis, acute self-resolving diarrheal syndrome, chronic diarrhea with failure to thrive, infant botulism, and asymptomatic carriage.

(Am J Dis Child 1983;137:271-274)

Author Affiliations
From the Sections of Infectious Diseases (Drs Thompson, Fisher, and Long) and Laboratories (Dr Gilligan), St Christopher's Hospital for Children, and the Departments of Pediatrics (Drs Thompson, Gilligan, Fisher, and Long) and Microbiology (Dr Long), Temple University School of Medicine, Philadelphia.

Footnotes
Presented in part at the 21st Interscience Conference on Antimicrobial Agents and Chemotherapy, Chicago, Nov 6, 1981.

Reprint requests to Section of Infectious Diseases, St Christopher's Hospital for Children, 2600 N Lawrence St, Philadelphia, PA 19133 (Dr Long).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Epidemiological Features of Clostridium difficile-Associated Disease Among Inpatients at Children's Hospitals in the United States, 2001-2006
Kim et al.
Pediatrics 2008;122:1266-1270.
ABSTRACT | FULL TEXT  

Clostridium difficile Isolation in Leukemic Children on Maintenance Cancer Chemotherapy: A Preliminary Study
Chiesa et al.
CLIN PEDIATR 1985;24:252-255.
ABSTRACT  

Clostridium difficile Toxin Associated with Chronic Diarrhea and Failure to Gain Weight
Liston
CLIN PEDIATR 1983;22:458-460.
ABSTRACT