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A Case With Resolution of Myoclonic Seizures After Treatment With a Low-Histidine Diet

I. Zachary Dyme, MD; Samuel J. Horwitz, MD; Barbara Bacchus, RD, MS; Douglas S. Kerr, MD

Am J Dis Child. 1983;137(3):256-258.

Abstract
• An infant with histidinemia had a myoclonic seizure disorder that was unresponsive to therapy with anticonvulsants. The seizures stopped promptly after a histidine-restricted diet was instituted. This case suggests that in some individuals with histidinemia, diet therapy may be effective. It is not known what distinguishes this case from previously reported cases in which diet therapy was not effective.

(Am J Dis Child 1983;137:256-258)

Author Affiliations
From the Department of Pediatrics, Case Western Reserve University and Rainbow Babies and Childrens Hospital, Cleveland.

Footnotes
Presented in poster form at the meeting of the Child Neurology Society, Minneapolis, Oct 15, 1981.

Reprint requests to Rainbow Babies and Childrens Hospital, 2101 Adelbert Rd, Cleveland, OH 44106 (Dr Dyme).

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