Prepubertal gynecomastia caused by an adrenal tumor. Diagnostic value of ultrasonography
R. M. Itami, G. M. Amundson, S. A. Kaplan and B. M. Lippe
Prepubertal gynecomastia is a rare disorder that may be associated with
adrenal or testicular tumors. An adrenal tumor causing a mixed
feminizing-virilizing syndrome in a 6-year-old boy was identified by
ultrasonography, whereas excretory urography failed to show any
abnormality. Highly elevated estrone concentrations were found in the
plasma, as were more modestly increased levels of estradiol, testosterone,
androstenedione, and 11-deoxycortisol. After removal of the tumor, all
hormonal concentrations returned to normal prepubertal levels.
