Robinow's syndrome. Partial primary hypogonadism in pubertal boys, with persistence of micropenis
P. A. Lee, C. J. Migeon, T. R. Brown and M. Robinow
We studied four patients with Robinow's syndrome. New findings included the
following: (1) normal pubertal virilization with persistence of micropenis;
(2) elevated basal serum follicle-stimulating hormone levels and a
hyperresponse of serum luteinizing hormone to gonadorelin hydrochloride
(Factrel) stimulation among postpubertal male patients, suggesting partial
primary hypogonadism; (3) normal 5 alpha-reductase and androgen receptor
activity in genital skin fibroblasts; and (4) normal to borderline adult
height.
