Clostridium difficile associated with pseudomembranous colitis. Occurrence in a 12-week-old infant without prior antibiotic therapy
S. P. Adler, T. Chandrika and W. F. Berman
In a previously healthy 12-week-old male infant with a two-week history of
poor feeding, colic, and bloody stools, pseudomembranous colitis developed.
No prior antibiotics were administered although the child had received
dicyclomine hydrochloride. Clostridium difficile and its toxin were
detected in the child's stool. Severe disseminated intravascular
coagulopathy developed; the patient required total colectomy but eventually
recovered. Clostridium difficile colonization has not, to our knowledge,
been previously documented in infantile pseudomembranous colitis.
