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Jeffrie Miller, MD; Anita Robinson, MD; Alan K. Percy, MD

Am J Dis Child. 1980;134(3):290-292.

Abstract
• Acute isoniazid poisoning is uncommon in children. Only 27 cases, to our knowledge, have been reported in the literature. Often, the first observation is of uncontrollable convulsions. The metabolic alterations are often striking and the treamtent has mainly been supportive, with the judicious use of pyridoxine hydrochloride in those cases in which a history of ingestion of isoniazid is obtained. The response to the administration of pyridoxine has been difficult to evaluate.

(Am J Dis Child 134:290-292, 1980)

Author Affiliations
From the Department of Pediatrics, Martin Luther King, Jr, General Hospital, and Charles R. Drew Postgraduate Medical School, Los Angeles.

Footnotes
Reprint requests to 1621 E 120th St, Los Angeles, CA 90059 (Dr Miller).

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