This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Effect of Early Diagnosis on Neurologic and Psychologic Salvage

Henrietta K. Sachs, MD; Donald A. McCaughran, PhD; Vita Krall, PhD; Irving H. Rozenfeld, MD; Nillawan Yongsmith, MD

Am J Dis Child. 1979;133(8):786-790.

Abstract
• Medical and psychological status of 166 patients previously treated for lead poisoning and of 22 sibling controls were evaluated. Maximum blood lead levels ranged from 40 to 471 µg/dL. Eighteen patients had definite symptoms, 32 had questionable symptoms, and 116 were asymptomatic. No patients developed seizures, other neurological sequelae, or abnormal nerve conduction velocity. No statistically significant relationship was found between blood lead concentration (PbB) and subsequent intellectual function. The mean IQ of the patient cohort was 87, approximately at the 50th percentile for inner-city schoolchildren in Chicago. Detection prior to encephalopathy and prompt detoxification were effective in preventing or minimizing sequelae despite high PbBs.

(Am J Dis Child 133:786-790, 1979)

Author Affiliations
From the Departments of Pediatrics (Drs Sachs and Rozenfeld), Psychology (Dr Krall), Rehabilitative Medicine (Dr Yongsmith), and the Siegel Institute for Communicative Disorders (Dr Rozenfeld), Michael Reese Medical Center, Chicago; and the Department of Biomathematics (Dr McCaughran), University of Washington, Seattle.

Footnotes
Reprint requests to 182 LaPier, Glencoe, IL 60022 (Dr Sachs).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

An Asymptomatic Middle-School-Age Boy With a Blood Lead Concentration of 173 {micro}g/dL
Chin and Charlton
CLIN PEDIATR 2004;43:189-192.