Endocrine abnormalities in thalassemia major
G. Costin, M. D. Kogut, C. B. Hyman and J. A. Ortega
Endocrine function evaluations in 16 patients with beta-thalassemia
indicate that hypogonadotropic hypogonadism, hypoparathyroidism, and
reduced adrenocorticotropic hormone reserve occur frequently, whereas
reduced growth hormone and thyroid reserve are less common manifestations.
Hemosiderosis-induced damage of the endocrine glands seems to be the main
cause for endocrine dysfunction in the patients studied.
