Congenital unilateral ichthyosis in a newborn
P. J. Lipsitz, F. Suser, S. Weinberg and E. Valderrama
Ichthyosiform erythroderma is a rare phenomenon occurring in about
1/300,000 live births. Congenital unilateral ichthyosis, described in this
case report, is a clinical variant of ichthyosis. Only five previous cases
have been reported. In the patient described in this report, superimposed
infection of the affected skin developed. Her immunologic system was
intact. She manifested failure to thrive, in spite of an adequate caloric
intake, and markedly delayed psychomotor development. This patient also
demonstrated absorption from the affected dermis of topically applied urea
hydrophilic base ointment. She died before her first birthday.
