The diagnosis of Leydig cell tumors in childhood
M. D. Urban, P. A. Lee, L. P. Plotnick and C. J. Migeon
We report the clinical and hormonal findings in two boys with isosexual
precocity secondary to Levdig cell tumor of the testis. The hormonal
profile at the initial evaluation was quite different in the two cases
suggesting differences in steroid biosynthesis by the tumors. These
differences indicate that a dexamethasone suppression test may be required
to differentiate between Leydig cell tumors and congenital virilizing
adrenal hyperplasia with adrenal rest tissue located within the testes.
