Inappropriate antidiuretic hormone secretion in premature infants with cerebral injury
F. M. Moylan, J. T. Herrin, K. Krishnamoorthy, I. D. Todres and D. C. Shannon
We describe 11 premature infants with the syndrome of inappropriate
antidiuretic hormone secretion (SIADH). The syndrome is far more common
than the single case report in the literature would indicate. All the
infants had either asphyxiation at birth, intracranial hemorrhage, or
meningitis. Of the nine children available for follow-up observation, seven
demonstrated serious neurological sequelae. The diagnosis of SIADH in the
premature neonate may be difficult to establish due to the complexity of
precipitating factors.
