Disseminated Intravascular DNA Thromboemboli: A Complication of Chemotherapy for Acute Lymphocytic Leukemia

doi:10.1001/archpedi.1978.02120280078017

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Vol. 132 No. 3, March 1978

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Disseminated Intravascular DNA Thromboemboli

A Complication of Chemotherapy for Acute Lymphocytic Leukemia

Stanley B. Smith, MD; Edward B. Blum, MD

Am J Dis Child. 1978;132(3):294-295.

Abstract

• Seven and one-half hours after receiving antileukemictherapy, an 11-year-old boy developed massive intravascularlysis of leukemic cells with subsequent pooling of DNA to formdisseminated intravascular thromboemboli. The DNA thromboemboliproduced neurologic symptoms and an alveolar capillary blockwith resultant dyspnea and death.

(Am J Dis Child 132:294-295, 1978)

Author Affiliations

From the Department of Pathology, Variety Children's Hospital, Miami, Fla.

Footnotes

Reprint requests to Department of Pathology, Variety Children'sHospital, 6125 SW 31st St, Miami, FL 33155 (Dr Smith).

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