Cystic fibrosis presenting with the meconium plug syndrome
B. J. Rosenstein
The meconium plug syndrome (MPS) is a common cause of low intestinal
obstruction in newborn infants. Usually, it is benign and not associated
with other intestinal dysfunction. We describe the cases of three infants
in whom there was intestinal obstruction consistent with the MPS and in
which cystic fibrosis (CF) was later documented. We suggest that there is
an association between the MPS and CF, and that the condition of all
infants with the MPS be evaluated for the possibility of both
Hirschsprung's disease and CF.
